First Response Early Result Pregnancy Test, 3 Count (Packaging & Test Design May Vary)

About the product

  • Our #1 best-selling pregnancy test [4]
  • The ONLY brand that can tell you 6 DAYS sooner than your missed period [1]
  • Over 99% accurate from the day of your expected period [2]
  • Detects all forms of the pregnancy hormone [5]
  • Read your results in just 3 minutes


From the manufacturer

Key Information
First Response Early Result Pregnancy Test
When you may be pregnant, the earlier you know, the better. Featuring First to Detect Technology, the First Response Early Result Pregnancy Test is sensitive enough to capture scant amounts of pregnancy hormones to give you a result 6 days sooner than your missed period. [1] No other brand can do that.

Features & Benefits

Quick and Accurate
First Response pregnancy tests are over 99% accurate from the day of your expected period. [2]

Detects 4 Major Forms of hCG
First Response Early Result detects all of the major pregnancy hormones commonly found in urine. Use as directed. [3]

Early Pregnancy Detection
First Response Early Result detects the pregnancy hormone six days sooner than the day of your missed period. [1]

Product description
Size:Pack of 1
When you may be pregnant, the earlier you know the better. Featuring First to Detect technology, the First Response Early Result Pregnancy Test is sensitive enough to capture scant amounts of pregnancy hormones to give you results 6 days sooner than your missed period. [1] Early Pregnancy Detection Matters [8] The first few weeks of pregnancy are critical to fetal development, so early prenatal care is important for a healthy birth weight and the baby’s survival. The sooner you know you’re pregnant, the sooner you can begin making healthy pregnancy choices for yourself and your baby that include diet, nutrition, and limiting your exposure to hazards. Things to Know About Testing Early Some pregnant women may not have detectable amounts of the pregnancy hormone in their urine on the day they use the test. The amount of pregnancy hormone increases as the pregnancy progresses. In laboratory testing, First Response detected the pregnancy hormone levels in 76% of pregnant women 5 days before their expected period, in 96% of pregnant women 4 days before their expected period, in >99% of pregnant women 3 days before their expected period, in >99% of pregnant women 2 days before their expected period, in >99% of pregnant women 1 day before their expected period, and in >99% of pregnant women on the day of their expected period.

Important information
Safety Warning
• Do not use after the expiration date stamped on the side of the carton. • Store in a dry place below 86⁰F (30⁰C). Do not freeze. • Keep out of the reach of children. • For in-vitro diagnostic use. Not to be taken internally. • Single-use device. Do not reuse.

Indications
Home pregnancy test kit. The FIRST RESPONSE Early Result Pregnancy Test is designed to detect hCG (human chorionic gonadotropin) as early as 6 days before your missed period (5 days before day of the expected period). You can use the test at any time of day. You do not have to use first morning urine. In general, your first-morning urine contains the highest level of pregnancy hormone.

Legal Disclaimer
1.FIRST RESPONSE detects the pregnancy hormone 6 days sooner than the day of your missed period (5 days before day of expected period). 2.>99% accurate at detecting typical pregnancy hormone levels. Note that hormone levels vary. 3.Minkin MJ. Embryonic development and pregnancy test sensitivity: the importance of earlier pregnancy detection. Women's Health (Lond Engl). 2009 Nov;5(6):659-67 Pharmacy Times OTC Survey 2013. Over 99% accurate in detecting the LH surge in laboratory studies. †Data on file

Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.

Directions
After reading instructions and when you are ready to perform the test, remove the test stick from the foil wrapper and take off the Overcap. Holding the test stick by the Thumb Grip with the Wide Absorbent Tip pointing downward and the Result Window facing away from your body, place the Wide Absorbent Tip in your urine stream for 5 seconds only. While still holding the stick with the Wide Absorbent Tip facing downward, replace the Overcap and lay the stick on a flat non-absorbent surface with the Easy-Read Result Window facing up. You may soon see a pink color moving across the Easy-Read Result Window Wait 3 minutes until reading result.

[1] First Response detects the pregnancy hormone 6 days sooner than the day of your missed period (5 days before the day of expected period).
[2] >99% accurate at detecting typical pregnancy hormone levels. Note that hormone levels vary.
[3] First Response Early Result and Gold Digital detect all of the major pregnancy hormone forms commonly found in urine. Use as directed.
[4] Nielsen AOC Diagnostics Database as of 7.15.17.
[5] US News and World Report, Pharmacy Times, Survey of Pharmacists’ OTC Recommendations, Ovulation Prediction, 2017.
[6] Sooner than without ovulation testing when directions are carefully followed.
[7] Over 99% accurate in detecting the LH surge in laboratory studies.
[8] Minkin MJ. Embryonic development and pregnancy test sensitivity: the importance of earlier pregnancy detection. Women's Health (Lond Engl). 2009 Nov, 5(6):659-67.

Top customer reviews

I decided to post some data about this FRER sensitivity for those of you who are like me wonders how the test reflects the actual HCG concentrations. I made serial dilutions of human recombinant HCG (Novarel), that I had some leftovers of after my IVF cycle. The dilutions were made with lab pipets, so the concentration should be pretty precise, and in the appropriate buffer (sorry for the details, that was my husband's urine) to model the amount of HCG in the urine for the test. Here are results (see photos attached too).

At 5 mU/ml, which is below the threshold of 6 mU/ml ( the sensitivity, claimed by the brand), the test is very-very faint. However, I would consider it positive, because just husband's urine only gives no second line at all (I do not have photo for this, we did it some time ago with our first unsuccessful transfer, when I had chemical pregnancy). 5 mU/ml in your first morning urine is equal about 10-15 mU/ml in blood, so this is comparable to 5-4 days before your missed period. Also, compare the 5 mU/ml results with my actual results for 8 days post transfer of 6-day blastocyst (last picture), two days later at 10dpt I had blood beta-HCG level of 38.

At 20 mU/ml we can see clear positive results. This is HCG level that you will have at your first day of missed period, and equals to about 40-60 mU/ml of beta-HCG in blood.

And only at 100 mU/ml we see the second line at the same brightness as the control line. I would say at this HCG level the FRER test reaches it's saturation point.

Also, I found out that you may use LH tests (used for ovulation detection) instead of HCG for the early results. LH tests are very sensitive, looks like even more sensitive than FRER (you can see how much darker the test line is for the 5 mU/ml sample). I could not find an information about what subunit of LH these tests are detecting, my understanding it is beta-subunit of LH which is nearly identical in structure to beta-subunit of HCG. Beta-HCG, however, has about 30 additional amino acids, so home pregnancy tests designed to pick up beta-HCG only, while home ovulation tests will pick up both. After ovulation and during pregnancy LH levels are down, so in my opinion you can easily use you LH leftover test to monitor HCG levels, at least to see how it doubles, for example.

Another observation for FRER, these tests tend to get darker with time. If your HCG levels are expected to be below or around the threshold (like day 6 post IVF transfer or so), and the test line does not show up, I suggest you keep the test for another 24 h and you may see faint positive later.

For those users, who claim about "false" positive FRER results. As my experiments with my husband's urine proved, if you do not have HCG, the test will be clear negative - no test line at all, only control line. If you see faint positive, which lately with another test disappeared, or if your period came, that means you had so called chemical pregnancy. It might be devastating, I understand, we had a chemical with our first failed IVF cycle. But this is a drawback of using very sensitive test, so just be prepared.

To summarize my experiment: FRER is very sensitive, it shows faint positive even below claimed threshold, however good positive results are at about 20 mU/ml, or your first day of missed period. I give only 4 stars for these tests because of the idiotic curved handle - it is completely unnecessary design, makes it difficult to lay flat, and takes more space in the drawer if you want to keep the used test for future reference.